News & Press
Edition 2 / June 2022
Small Molecules Platform > CordenPharma Fribourg Inaugurates Expanded Drug Product Manufacturing Facility
Edition 2 / June 2022
Author
Dr. Stephen Houldsworth,
VP, Global Head of Platform Management & Marketing,
CordenPharma International
On Friday May 20th CordenPharma Fribourg (CH) hosted a ribbon cutting ceremony to inaugurate their newly-expanded drug product
manufacturing facility.
On Friday May 20th, Yvan Liard, Managing Director of CordenPharma Fribourg, was joined by CEO Dr. Michael Quirmbach and Olivier Curty, Government Councilor of Canton Fribourg (CH) at our recently acquired Fribourg facility to officially open the expansion of a new drug product manufacturing facility. They were joined at the site by a selection of site employees, customers and contractors to enjoy speeches, aperitifs and a tour of the newly constructed space.
This ribbon cutting ceremony marked the final completion of the design and build cycle that started in early 2019. The rapid construction was only possible thanks to a unique modular design concept that allows for the efficient addition of manufacturing lines when capacity or customer demands require it. Thus the Fribourg expansion resulted in the construction of an outer shell in which individual modular production sections can be easily incorporated. In this first phase, 50% of the available production space was completed with bulk manufacturing and final packaging lines ideal for the primary and secondary packaging of tablets or capsules into blisters or bottles for worldwide markets.
After an initial internal operational approval granted in August 2019 and full financial approval received in October 2019, the compressed construction timeline was possible due to the support of local economic promotion groups and rapid receipt of building permits, allowing shovels to break ground in July 2020, despite the unwelcome global effects of the COVID-19 pandemic! Construction took a little over 12 months to complete, thanks not only to the unique modular design but also the environmental and sustainability choices made in the design phase. This also reinforces the growing trend that a focus on sustainability can and should be factored into CDMO and pharmaceutical construction projects, without the need to compromise on time or budget!
Since September 2021 the newly constructed manufacturing facility has been fully operational, which includes an expanded raw material, intermediate and final drug product warehousing operation incorporating AGVs (Automated Guided Vehicles) and a new automatic service elevator to bring materials to the production floors, all fully integrated into the site’s SAP inventory system. Additional technologies include a Fette encapsulation machine and associated compounding / blending area, one new Uhlmann blister packaging line, and one new Uhlmann bottle packaging line with full serialization and aggregation capabilities. In total the expansion created 33,000 m³ of new pharmaceutical manufacturing space.
With this facility expansion we can now easily double our previous production capacities for tablets and hard shell capsules at the Fribourg facility, while in the meantime building for the future. Although the expansion does not include additional service offerings, its unique design does grant the space to consider bringing in new manufacturing modalities to complement the current extensive Oral Solid Dosage (OSD) capabilities already available at the site. This setup allows us to meet the growing needs of our expanding customer base.
Finally, we would like to acknowledge the role that the former site owners Vifor Pharma played in this expansion. Without their original vision for the site, the planning phase for the project would not have been initiated or executed as concisely. Clearly the capabilities and new capacities that were created as part of this expansion greatly contributed to CordenPharma’s decision to acquire the site in February 2022.
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Celebrations included a garden party with a festive banquet of foods from Italy, Germany, France, & US, games, marshmallow roasting, custom beer steins and other 15 Year gifts, and balloons stuffed with prizes. All employees then heard a speech from Managing Director Brian McCudden and COO Dr. Lee Newton.
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Celebrations were split into 3 groups to cover all shifts and included a festive room with a 3 course buffet meal, 15 Year custom gift bags with locally-brewed beer, and a welcome speech by Site Business Development Christina Simons and CEO Dr. Michael Quirmbach.
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Celebrations included a garden party with food trucks, table games, a pub quiz with team prizes, instant cameras for a photo collage, and 15 Year gifts. Guests included the CPI Global Compliance Team, Allessa GmbH, Weylchem Innotec GmbH, and Walter Krebs GmbH, with speeches by Head of Operations Dr. Karsten Meyenberg and CFO Heiko Serwe.
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Celebrations included a garden party with a “Burgundy” aperitif dinner, food trucks for lunch, a fun photo booth for taking 15 Year souvenirs, and speeches by Managing Director Yves Michon and CordenPharma Chief Quality & Compliance Officer Will Cashin.
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Celebrations continued 4 times throughout the day & night to cover all shifts, and included a multi-course German lunch or dinner with brezel, speeches by Managing Director Fabrizio Fiordigiglio and VP of Sales Dr. Mimoun Ayoub, followed by a festive garden gazebo for the 15 Year gift distribution of Prosecco and backpacks.
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Celebrations included a boat ride to Brussels City Center, followed by 3 groups taking guided bike or walking tours of secret places along the canal or the Tour & Taxis building. The party finished with a BBQ dinner and speeches from Managing Director Dr. Jean-Luc Dewez and VP General Counsel Nicolas Reischer.
Brittany Hayes joined CordenPharma as Director, Global Highly Potent & Oncology Platform in October 2021, bringing over 20 years of extensive experience in the areas of contract manufacturing (Drug Substance & Drug Product), pharmaceutical and API development, business development, contract management, and organic chemistry.
Prior to joining CordenPharma, Brittany held leadership positions at various Contract Development & Manufacturing Organizations (CDMOs) including Recro, Regis Technologies, DSM/Patheon/Thermo Fisher, Formex, Ricerca, and Azopharma. Most recently, Brittany was Applied Technology Director at Recro, where she was responsible for managing the proposal evaluations and development team, providing technical support to the BD team, creating training for new service offerings, and enhancing new client onboarding & knowledge transfer by liaising with business development executives, technical operations personnel, and project managers. Brittany excels at driving technical decision-making for successful pharmaceutical product development.
Brittany earned her Ph.D. in organic chemistry from Wake Forest University (Winston-Salem, NC) and her B.S. degree in Chemistry from Emory University (Atlanta, GA). She also was an American Heart Association postdoctoral fellow at the University of Illinois at Chicago, Department of Medicinal Chemistry & Pharmacognosy. Brittany has been an active member of the American Chemical Society since 1995.