Technologies / Processes

Reactions

  • >> Acetylation
  • >> Acylation
  • >> Enantioselective Synthesis
  • >> Catalytic Hydrogenation
  • >> (homogeneous, heterogeneous)
  • >> Suzuki Coupling
  • >> Sharpless Epoxidation
  • >> Grignard Reaction
  • >> Mitsunobu Reaction
  • >> Organometallic Reactions
  • >> Phosphorylation
  • >> Polymerisation
  • >> Oxidation (swern/tempo)
  • >> Wittig Reaction

Equipment Details

Equipment for Scale-up & Commercial Production

  • >> Kilo-lab suites for small-scale cGMP requirements
  • >> Equipment capacity ranging from 20 to 160 L
  • >> Reactor suites
    • >> Reactor capacity: 60 to 2500 L (total reactor volume 27 m3)
    • >> Hydrogenation suite 200 to 1000 L, 20 bar
    • >> Temperature range: -90°C to 160°C
  • >> Drying Suites
    • >> Conical Dryer
    • >> Filter Dryers
    • >> Vacuum Tray Dryers
    • >> Lyophilization
  • >> Milling / Screening Suite
  • >> Large-scale Chromatography

Special Equipment

  • >> Preparative HPLC equipment (reversed phase; normal phase) up to 30 cm columns
  • >> MPLC Equipment
  • >> Fully Automated & GMP Peptide Synthesizer
  • >> Lyophilisation

Capacities

Reaction Vessels (Multi-Purpose & Dedicated Equipment)

  • >> From 20 L to 2500 L
  • >> Pilot Plant for kg-scale

Other Specialties

Sales with Global Customer Base

  • >> More than 100 active customers from start-up to large biotech or pharma

Project Management

  • >> Critical chain project management (CCPM) & stage gate approach
  • >> Many projects in various stages of development & commercialization

R&D

  • >> Successful track record for many complex projects, production of multiple R&D samples & reference standards
  • >> Parallel reaction station (LAIX)
  • >> Flexi-Lab (systag)
  • >> Easymax-Optimax system

Production

  • >> Dedicated suites for biodegradable polymers

Quality

  • >> Successful track record for many projects & inspections
  • >> Experience in consulting customers in QA/QC/RA questions