CORDENPHARMA COLORADO FACILITY CAPACITIES

Technologies / Processes

  • >> Hydrogenation / Hydrogenolysis
  • >> Cryogenic chemistry
  • >> Pyrophoric chemistry
  • >> Chiral chemistry
  • >> Pegylation chemistry
  • >> Pre-formulated liquid products
  • >> Peptides
  • >> Peptide synthesis (10,000 L)
  • >> Cyclization (up to 12,000 L)
  • >> De-aggregation chemistry (Pseudoprolines, DMB)
  • >> Ion exchange (size exclusion chromatography)
  • >> Ultrafiltration, Diafiltration, TFF
  • >> Precipitation of peptides (allows larger batches)
  • >> High & Mid Pressure preparative chromatography
  • >> Lab equipment design (mimics plant design)
  • >> Special low endotoxin / bioburden engineering setup for oligo manufacturing
  • >> PAT (oligo manufacturing)

Equipment Details

  • >> Large-scale
  • >> Pilot plant
  • >> Peptide & oligo purification (up to 100 cm column)
  • >> Highly active compounds
  • >> OligoPilot Akta 100, OligoPilot 400 & OligoProcess
  • >> Extremely large tank farm

Capacities

  • >> One of the largest vessel capacities in the API Contract Manufacturing arena
  • >> Nearly 470,000 L vessel volume available

Capacities

  • >> Enfuvirtide
  • >> Valcyte
  • >> Cytovene
  • >> Linaclotide
  • >> Rocaltrol
  • >> Highly Active Peptide A
  • >> Protease Inhibitor Intermediate